Danish pharmaceutical giant Novo Nordisk is undergoing substantial strategic recalibration, marked by a pivotal leadership transition and a revised financial outlook. The company recently announced a new CEO while simultaneously lowering its full-year sales and profit projections, primarily attributing the revised forecast to intensified competitive pressures and slower-than-anticipated market expansion for its key obesity and diabetes medications in the United States.
- Novo Nordisk announced Maziar Mike Doustdar as its new President and CEO, effective August 7.
- The company significantly lowered its full-year sales growth forecast to 8%-14% and operating profit growth to 10%-16%.
- This revision is primarily due to intensified competitive pressures and slower-than-anticipated U.S. market expansion for key obesity and diabetes medications.
- Novo Nordisk’s shares experienced a substantial intraday decline of up to 26%, closing down 23% in London, following these announcements.
- The company is slated to release its comprehensive second-quarter results on August 6.
Leadership Transition at the Helm
Maziar Mike Doustdar is set to take over as President and CEO on August 7, succeeding Lars Fruergaard Jørgensen, whose unexpected departure took place in May. A seasoned veteran, Doustdar has been with Novo Nordisk since 1992, bringing extensive executive experience from international operations, most recently as Executive Vice President of International Operations. Helge Lund, Chairman of the Board, conveyed strong confidence in Doustdar’s ability to steer the company through its next phase of growth. In his inaugural statement, Doustdar underscored an immediate emphasis on high performance and a steadfast commitment to advancing patient-centric innovation.
Revised Financial Projections
In the wake of these announcements, Novo Nordisk’s shares saw a sharp decline, plummeting as much as 26% intraday and closing 23% lower in London. The company has adjusted its full-year sales growth forecast to a range of 8% to 14%, a significant reduction from its previous estimate of 13% to 21%. Concurrently, projected operating profit growth has been revised to between 10% and 16%, down from the earlier 16% to 24% range.
This downward revision was primarily attributed to a more subdued outlook for the second half of the year, specifically impacting sales of its flagship medications, Wegovy and Ozempic, in the U.S. market. Contributing factors include the ongoing proliferation of GLP-1 compound medications, a slower-than-anticipated market expansion for Novo Nordisk’s products, and intensified competition within this critical therapeutic area.
Market Challenges and Outlook
Novo Nordisk has contended with significant challenges in bolstering Wegovy sales within the U.S. market, largely due to intense competition from compound drug manufacturers. This challenge was further exacerbated by a recent U.S. Food and Drug Administration (FDA) decision concerning the drug’s supply status. The company had previously adjusted its 2025 guidance in May, following a period of lower-than-expected quarterly sales. Despite a year-to-date stock value decline exceeding 42%, Novo Nordisk projects a decrease in competitive pressures from what it terms “imitator drugs” in the latter half of the year. The firm also faces scrutiny regarding the clinical trial results of CagriSema, its prospective obesity treatment, as it navigates an increasingly competitive and rapidly evolving market landscape. The company is slated to release its comprehensive second-quarter results on August 6.

Jonathan Reed received his MA in Journalism from Columbia University and has reported on corporate governance and leadership for major business magazines. His coverage focuses on executive decision-making, startup innovation, and the evolving role of technology in driving business growth.